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[MS] MALDI-TOF 분석에서 분석시료 종류에 따른 Matrix 선택.

Matrix
Application
α-cyano-4-hydroxycinnamic acid (CHCA)
 Peptide/proteins <10,000 Da
Sinapinic acid (3,5-Dimethoxy-4-hydroxy cinnamic acid)
 Peptides and proteins >10,000 Da
 2,4,6-Trihydroxy acetophenone(THAP)
 Small oligonucleotides <3,500 Da, acidic carbohydrates, acidic glycopeptides, acid sensitive compounds
 3-hydroxypicolinic acid (3-HPA) in ammonium citrate
 Large oligonucleotides >3,500 Da
 2,5-dihydroxybenzoic acid (2,5-DHB)
 Peptides, neutral or basic carbohydrates, glycolipids (negative ions), polar and non-polar synthetic polymers, small molecules
 2,5-dihydroxybenzoic acid and 5-methoxysalicylic acid (DHBs)
 Peptides and proteins >10,000 Da, glycosylated proteins
 Dithranol and Ag TFA
 Aromatc polymers
 trans-3-indoleacrylic acid (IAA)
 Non-polar polymers
 1-(4-hydroxyphenylazo)-benzoic acid (HABA)
 Proteins, polar and nonpolar synthetic polymers
[이 게시물은 이매스님에 의해 2014-01-03 17:10:54 지식나눔터에서 이동 됨]
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